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So far Circle Pharma has created 34 blog entries.

Circle Pharma Announces Appointment of David Spellmeyer, PhD, as Chief Scientific Officer

2017-11-20T16:35:38+00:00 November 20th, 2017|Press Releases|

SOUTH SAN FRANCISCO, Calif. – (BUSINESS WIRE) – Circle Pharma, Inc., a developer of macrocycle therapeutics, today announced that David Spellmeyer, PhD, has been appointed as its chief scientific officer.

“His deep experience in rational drug design and discovery is an excellent fit for Circle as we extend our platform for macrocycle discovery and advance our therapeutic pipeline towards the clinic.”

Dr. Spellmeyer brings over 25 years of broad industrial experience to […]

Circle Pharma announces expansion of Series A financing and appointment of James C. Lu to its board

2017-09-25T14:41:44+00:00 April 5th, 2017|Press Releases|

Funds will be used to advance Circle’s computational and synthetic chemistry platform for macrocyclic peptide therapeutics Circle Pharma, Inc. today announced that it has completed an expansion of its Series A financing, with new investors W.I. Harper Group, Elements Partners, LLC, Whitesun Healthcare Ventures Limited and LifeForce Capital joining the round. Mission Bay Capital led Circle’s Series A, with Pfizer Inc. (NYSE:PFE), ShangPharma Investment Group, Ltd. and a syndicated group of in […]

Circle Pharma announces Series A financing and appoints Walter H. Moos, Ph.D., to its board

2017-09-25T09:59:00+00:00 December 21st, 2016|Press Releases|

Circle Pharma, Inc. today announced a Series A financing round in which it has issued over $4.5M of shares of Series A Preferred Stock. The financing was led by Mission Bay Capital, with Pfizer Inc. (NYSE:PFE), ShangPharma Investment Group, Ltd. and a syndicated group of individual investors joining the round. In connection with the financing, Walter H. Moos, Ph.D., representing ShangPharma, has joined the Circle Board of Directors.

“We are delighted with the participation of such high calibe […]

Passive Membrane Permeability in Cyclic Peptomer Scaffolds Is Robust to Extensive Variation in Side Chain Functionality and Backbone Geometry

2017-11-09T11:56:17+00:00 October 3rd, 2016|by our Team Members, Publications|

Synthetic and natural cyclic peptides provide a testing ground for studying membrane permeability in nontraditional drug scaffolds. Cyclic peptomers combine the stereochemical and geometric complexity of peptides with the functional group diversity accessible to peptoids.
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Circle Pharma enters into an agreement with Pfizer to build screening library of macrocyclic peptides

2017-09-25T12:43:52+00:00 September 12th, 2016|Press Releases|

CirclePharma, Inc., today announced that it will apply its computational design and synthetic chemistry platform to design and create a physical screening library of novel macrocyclicpeptides. Once completed, the library is initially expected to comprise several hundred macrocycles that will be designed to potentially disrupt bioactive conformations commonly found in protein-protein interactions known to drive disease processes, and will deploy backbone scaffolds screened in silica for intrinsic […]