Circle Pharma Appoints Alan Ashworth, PhD, FRS and Bruce Stillman, PhD, FRS to Its SAB
Renowned scientists Dr. Bruce Stillman and Dr. Alan Ashworth join Nobel laureate Dr. William Kaelin on Circle Pharma's Scientific Advisory Board.[...]
Circle Pharma Appoints Rajinder Singh, PhD as its Chief Science Officer
Circle Pharma Appoints Rajinder Singh, PhD as its Chief Science Officer[...]
Circle Pharma Appoints William G. Kaelin Jr. MD as Chair of Its Scientific Advisory Board
Circle Pharma has appointed 2019 Nobel Laureate William G. Kaelin Jr., MD as its lead science advisor and chair of its SAB.[...]
Circle Pharma raises $45 Million in Series B Financing
Circle Pharma closes $45M series B financing led by The Column Group to support its macrocycle drug development work. [...]
Circle Pharma Congratulates Dr. William G. Kaelin, Jr., MD on Award of Nobel Prize
Circle Pharma congratulates 2019 Nobel laureate Dr. Bill Kaelin. Dr. Kaelin advises Circle on its work to develop cyclin inhibitors for cancer., [...]
Peptide Therapeutics Near the Sweetest Spots
Peptide therapeutics would seem to occupy a sweet spot between small molecules and biologics. Small molecules, which represent the majority of clinical drugs, preferentially bind hydrophobic pockets or cavities, [...]
Circle Pharma’s work with Pfizer yields new macrocyclic peptides
Circle Pharma Inc. said its first collaboration with Pfizer Inc. has led to the identification of a series of bioavailable macrocyclic peptides capable of acting as potent and cell-permeable modulators of CXCR7. [...]
Circle Pharma Announces Publication in Journal of Medicinal Chemistry of Results from Collaboration with Pfizer Inc.
Results from its collaborative work with Pfizer to develop a potent and orally bioavailable macrocycle modulator have been published [...]
Circle Pharma Announces Appointment of David Spellmeyer, PhD, as Chief Scientific Officer
David Spellmeyer, PhD, has been appointed as Circle Pharma's chief scientific officer [...]
Practical Medicinal Chemistry with Macrocycles – Design, Synthesis, and Case Studies
Cyclic peptide natural products and their synthetic mimics have gained prominence as potential sources of next‐generation therapeutics and biological probes. The size and structural complexity of these compounds sets them apart from common synthetic drugs.
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