Matthew P. Jacobson, Ph.D.

Co-Founder and Chief Scientific Officer

Matthew P. Jacobson, Ph.D., is a co-founder of Circle Pharma and a member of Circle’s Board of Directors. Matt is a leading authority in computer-aided drug design and computational structural biology and biophysics and the author of more than 200 research publications. He is Professor Emeritus in the Department of Pharmaceutical Chemistry at UCSF, and in addition to Circle Pharma is a co-founder of companies including Global Blood Therapeutics, Relay Therapeutics, Terremoto and Nine Square Therapeutics. Matt is also a venture partner at Apple Tree Partners.
Matt earned his Ph.D. in physical chemistry at MIT and completed post-doctoral research at Oxford and Columbia. As a faculty member at UCSF, he received the NSF CAREER Award, an Alfred P. Sloan Fellowship and several UCSF School of Pharmacy teaching awards. He has served on the editorial boards of several journals, including Biochemistry, PLoS Computational Biology, and Structure.

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