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Home
About Us
Our Mission and Vision
Meet the Team
Board of Directors
Scientific Advisory Board
Investors
Our Science
About Macrocycles
Introducing MXMO
TM
Our Pipeline
Clinical Trials
Publications
What’s New
Press Releases
Events
Publications
Publications
CID-078, a First-in-Class Oral Macrocycle CyclinA/B-RxL Inhibitor, Demonstrates Anti-Tumor Activity in E2F-driven Cancers
October 23, 2024
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Publications
Orally bioavailable Cyclin A/B RxL macrocycle has antitumor effect in SCLC and NSCLC cell line derived (CDX) and patient derived xenograft (PDX) models
September 9, 2024
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Publications
Permeable macrocyclic peptide Cyclin A/B RxL inhibitors: synthetic development, SAR and in vivo target validation
August 22, 2024
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Publications
Expanding Circle Pharma’s Discovery Synthesis Toolbox for Permeable Macrocycles With Automatable Bioisoteric Cyclization Chemistries
August 12, 2024
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Publications
Application of a Semi-Automated Solid-Phase Synthesis Platform for the Discovery of Macrocyclic Peptide Cyclin A RxL Inhibitors
August 12, 2024
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Publications
Novel orally bioavailable macrocycles that target cyclin A and B elicit antitumor activity in breast cancer patient-derived xenograft models
October 23, 2023
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