SOUTH SAN FRANCISCO, CA, September 28, 2026 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced the promotion of Marie Evangelista, Ph.D., to chief scientific officer and the appointment of Mary Ellen Sillivos as senior vice president and head of human resources. The appointments strengthen Circle’s leadership team as the company advances its pipeline of next-generation targeted macrocycle therapeutics and prepares for its next stage of growth.
“Marie has been instrumental in shaping our research strategy and advancing our pipeline since joining Circle, and her promotion to chief scientific officer reflects both the impact she has already made and the important role she will play as we continue to build our portfolio of novel macrocycle therapeutics,” said David J. Earp, J.D., Ph.D., president and chief executive officer of Circle Pharma. “We are also delighted to welcome Mary Ellen, whose extensive experience building and supporting organizations across multiple stages of growth will be invaluable as we continue to evolve Circle and expand the capabilities needed to execute on our ambitions.”
“Circle has built a differentiated approach to macrocycle drug discovery with the potential to address important cancer targets that have historically been beyond the reach of conventional small molecules,” said Dr. Evangelista. “I am excited to take on this expanded role and continue working with our talented team to translate the capabilities of our MXMO™ platform into a pipeline of meaningful new therapies for patients with cancer.”
“I am thrilled to join Circle at such an important point in the company’s evolution,” said Ms. Sillivos. “I look forward to partnering with David and the leadership team to build the organization, culture and capabilities that will support Circle as it continues to grow and advance its pipeline.”
About Marie Evangelista, Ph.D., chief scientific officer
Dr. Evangelista joined Circle in 2024 as senior vice president and head of cancer biology. Previously, she held the position of vice president of oncology at Recursion, leading the oncology group and advancing their internal pipeline while establishing key partnerships with Genentech/Roche and Bayer. Before that, she spent 18 years at Genentech, directing precision oncology programs focused on cell cycle, tumor metabolism, and targeted therapy resistance. She played a crucial role in developing GDC-6036 (Divarasib), now in Phase 3 trials. Dr. Evangelista earned her Ph.D. from Queen’s University in Canada, receiving the NSERC Doctoral Prize and the Governor General’s Gold Medal. She completed postdoctoral training at Genentech with Fred de Sauvage. Dr. Evangelista has published over 40 papers in top journals, including Science, Cell, and Nature Biotechnology, and holds a dozen patents.
About Mary Ellen Sillivos, senior vice president and head of human resources
Mary Ellen Sillivos brings over thirty years of experience in the biotech and biopharmaceutical industry. Prior to joining Circle, Ms. Sillivos held several leadership positions including serving as vice president, human resources at Quince Therapeutics and Cortexyme. Previously, she held positions of increasing responsibility, including vice president, human resources at Dermira and executive director, human resources at Affymax. She has broad experience in all aspects of HR operations, specifically within early stage and start-up companies through commercialization. Ms. Sillivos attended the University of San Francisco and is a certified Senior Professional in Human Resources (SPHR).
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer and other serious illnesses. Circle Pharma’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Rob Lauzen
Circle Pharma
Robert.Lauzen@circlepharma.com
Financing led by The Column Group with participation from Nextech Invest, RA Capital Management, Euclidean Capital and a strategic investment from Eli Lilly and Company
CID-165, a first-in-class oral macrocyclic cyclin D1 RxL inhibitor, is expected to enter clinical development in Q1 2027 for patients with ER+ breast cancer
CID-165 has demonstrated robust anti-tumor activity in cyclin D1-driven preclinical cancer models, including in combination with CDK4/6-dual inhibitors, CDK4-selective inhibitors and endocrine therapies
SOUTH SAN FRANCISCO, CA, September 16, 2026 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced an oversubscribed $92.5 million Series E financing. The financing was led by The Column Group and included participation from other existing and new investors including Nextech Invest, RA Capital Management, Euclidean Capital and Eli Lilly and Company. Proceeds from the financing will drive the advancement of CID-165, a first-in-class oral macrocyclic cyclin D1 RxL inhibitor, through early clinical development for ER-positive breast cancer, while also supporting the continued development of Circle Pharma’s broader pipeline of cyclin-targeted macrocycles.
“This financing marks a significant milestone as we execute upon our vision of harnessing the power of macrocycles to transform the treatment of cancer,” said David J. Earp, J.D., Ph.D., president and chief executive officer of Circle Pharma. “Momentum around our cyclin D1 program has continued to build as CID-165 advances toward the clinic. We believe CID-165 has the potential to become a new backbone therapy for ER-positive breast cancer and this financing provides us with the resources to generate meaningful clinical data to validate that potential. Progress across our pipeline underscores the ability of our platform to generate first-in-class compounds across the previously undrugged family of cyclins, the master regulators of the cell cycle. We are grateful for the commitment and support of our existing and new investors.”
“Cyclin D1 is a well-established driver of cancer, especially in ER-positive breast cancer where there is a lineage dependency on this cyclin, but directly targeting it has remained a longstanding challenge,” said Marie Evangelista, Ph.D., chief scientific officer at Circle Pharma. “CID-165 is designed to selectively disrupt the interaction between cyclin D1 and retinoblastoma protein, providing a novel approach to directly targeting this fundamental driver of tumor growth. The robust activity we have observed across preclinical models in ER-positive breast cancer, both as a monotherapy and in combination with established treatments, gives us strong conviction in the potential of CID-165 as we prepare to advance the program into the clinic in the first quarter of 2027.”
About Cyclin D1 and CID-165
Cyclin D1 is a regulatory protein that plays a crucial role in cell cycle progression and is dysregulated in some malignancies, including ER-positive breast cancer and certain lymphomas. In these cancers, dysregulated cyclin D1 drives abnormal cell proliferation through its inactivation of the tumor suppressor retinoblastoma protein (Rb) leading to uncontrolled cell division. In preclinical studies, CID-165 has been shown to potently and selectively disrupt the cyclin D1-Rb interaction allowing Rb to remain active and suppress cancer cell proliferation. CID-165 is a first-in-class, orally bioavailable, macrocyclic cyclin D1 RxL inhibitor that has demonstrated robust anti-tumor activity in cyclin D1-driven preclinical cancer models, including in combination with other therapies such as CDK4/6-dual inhibitors, CDK4-selective inhibitors and endocrine therapies.
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer and other serious illnesses. Circle Pharma’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Rob Lauzen
Circle Pharma
Robert.Lauzen@circlepharma.com
SOUTH SAN FRANCISCO, CA, March 18, 2026 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced upcoming presentations at the American Association for Cancer Research (AACR) Annual Meeting, taking place April 17-22 in San Diego.
Presentations will highlight progress across Circle Pharma’s cyclin inhibitor programs and its MXMO™ platform, including preclinical findings and an oral plenary highlighting early clinical activity for CID-078, a first-in-class, orally bioavailable macrocyclic cyclin A/B RxL inhibitor currently being evaluated in a Phase 1 clinical trial for patients with advanced solid tumors.
Details of the presentations are as follows:
Title: Early clinical activity from the phase 1 evaluation of CID-078, a novel Cyclin A/B-RxL inhibitor, in patients with advanced solid tumors
Session Title: Clinical Trials Plenary Session: New Frontiers in Precision Oncology
Date & Time: Sunday, April 19, 1:00-3:00 p.m. PST
Presenter: Afshin Dowlati, M.D.
Title: Discovery of CID-078, a first-in-class oral macrocycle cyclin A/B-RxL inhibitor, for the treatment of cancers with RB1 loss or hyperactivated E2F
Session Title: New Drugs on the Horizon: Part 3
Date & Time: Monday, April 20, 10:15-11:45 a.m. PST
Presenter: Marie Evangelista, Ph.D.
Title: Orally Bioavailable Peptide Macrocycles Disrupting Intracellular Protein-Protein Interactions: Selective Inhibitors of the RxL-binding Site of Cyclin Family Proteins
Session Title: Chemistry to the Clinic Part 3 of 4: Novel Modalities, Targets, and Mechanisms in Drugging Oncogenic Pathways
Date & Time: Saturday, April 18, 12:30-2:00 p.m. PST
Presenter: Justin Shapiro, Ph.D.
About CID-078, Circle Pharma’s Oral Cyclin A/B RxL Inhibitor Program
CID-078 is an orally bioavailable macrocycle with dual activity blocking protein-protein interactions between both cyclins A and B and key substrates that bind to them via conserved RxL motifs. CID-078 selectively targets tumor cells with oncogenic alterations that cause cell cycle dysregulation, including alterations in the tumor suppressor RB1. In preclinical studies, Circle Pharma’s cyclin A/B RxL inhibitors have been shown to potently and selectively disrupt the protein-to-protein interaction between cyclins A and B and their key substrates and modulators, including E2F (a substrate of cyclin A) and MYT1 (a modulator of cyclin B). Preclinical studies have demonstrated the ability of these cyclin A/B RxL inhibitors to cause single-agent tumor regressions in multiple in vivo models. A multicenter Phase 1 clinical trial (NCT06577987) is currently enrolling patients with advanced solid tumors harboring RB1 alterations.
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer and other serious illnesses. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
josie@1abmedia.com
Investors:
Matt Clawson
1AB
matt@1abmedia.com
Research describes progress of discovery-stage macrocycles to orally bioavailable compounds targeting E2F-high and G1-S checkpoint-compromised cancers
SOUTH SAN FRANCISCO, CA, March 12, 2026 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced publication of research in the Journal of Medicinal Chemistry titled, “Orally Bioavailable Cyclin A/B RxL Inhibitors: Optimization of a Novel Class of Macrocyclic Peptides That Target E2F-High and G1-S-Checkpoint-Compromised Cancers.” The paper is included in the journal’s special issue on Peptide Therapeutics.
The publication builds on the company’s August 2025 Journal of Medicinal Chemistry paper titled, “Discovery of Cell-Permeable Macrocyclic Cyclin A/B RxL Inhibitors that Demonstrate Antitumor Activity,” which described the first cell-permeable macrocyclic cyclin A/B RxL inhibitors and provided initial in vivo proof-of-concept efficacy.
“This publication demonstrates the capability of our MXMO™ macrocycle platform to bring forward orally bioavailable macrocycles against therapeutic targets that have been refractory to small molecule chemistry,” said James Aggen, Ph.D., vice president of medicinal chemistry at Circle Pharma. “Our earlier work established that the cyclin A/B hydrophobic patch was druggable with macrocycles. This new research demonstrates these molecules can be delivered orally with compelling in vivo activity.”
Cyclins A and B regulate cell cycle progression by recruiting substrates through an RxL-mediated interaction. In cancers characterized by RB1 loss or elevated E2F activity – including nearly all small-cell lung cancers – this pathway becomes dysregulated, driving uncontrolled tumor growth. Rather than inhibiting CDK catalytic activity, Circle Pharma’s approach disrupts the protein-protein interactions between cyclins A and B and their RxL-containing substrates, selectively killing E2F-high tumor cells.
CID-078, Circle Pharma’s oral cyclin A/B RxL inhibitor is currently being evaluated in a multi-center Phase 1 clinical trial in patients with advanced solid tumors (NCT06577987).
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Matt Clawson
1AB
SOUTH SAN FRANCISCO, CA, February 17, 2026 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced management will participate in upcoming investor conferences in February and March, as follows:
Oppenheimer 36th Annual Healthcare Life Sciences Conference
Presentation Date/Time: 3:20 p.m. ET, Wednesday, Feb. 25, 2026
Participants: David J. Earp, J.D., Ph.D., president and chief executive officer; Anne Borgman, M.D., chief medical officer; Rob Lauzen, chief financial officer
Location: Virtual
TD Cowen 46th Annual Health Care Conference
Date: Monday, March 2, 2026
Participants: David J. Earp, J.D., Ph.D., president and chief executive officer; Anne Borgman, M.D., chief medical officer; Rob Lauzen, chief financial officer
Location: Boston
Leerink Global Healthcare Conference
Date: Wednesday, March 11, 2026
Participants: David J. Earp, J.D., Ph.D., president and chief executive officer; Rob Lauzen, chief financial officer
Location: Miami
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler, 1AB
Investors:
Rob Lauzen, Circle Pharma
Robert.Lauzen@circlepharma.com
SOUTH SAN FRANCISCO, CA, January 5, 2026 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced that David J. Earp, J.D., Ph.D., president and chief executive officer, will present at the 44th Annual J.P. Morgan Healthcare Conference on Wednesday, January 14, 2026 at 5:00 p.m. PT.
Dr. Earp will provide an overview of the company’s pipeline, including CID-078, a first-in-class oral macrocyclic cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors, and CID-165, a first-in-class oral macrocyclic cyclin D1 RxL inhibitor, with potential applications in malignancies, including ER-positive breast cancer and lymphomas.
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Steve Klass
1AB
SOUTH SAN FRANCISCO, CA, December 17, 2025 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced the nomination of CID-165, a first-in-class, orally bioavailable macrocyclic cyclin D1 RxL inhibitor, as the development candidate for its second oncology program.
Cyclin D1 is a regulatory protein that plays a crucial role in cell cycle progression and is overexpressed or translocated in malignancies, including ER-positive breast cancer and lymphomas. In these cancers, cyclin D1 drives cell proliferation by binding to the tumor suppressor retinoblastoma protein (Rb) leading to uncontrolled cell division. In preclinical studies, CID-165 has been shown to potently and selectively disrupt the cyclin D1-Rb interaction allowing Rb to remain active and suppress cancer cell proliferation. CID-165 demonstrates robust anti-tumor activity in cyclin D1-driven preclinical cancer models including in combination with other therapies such as CDK4/6-dual inhibitors, CDK4-selective inhibitors, and endocrine therapies.
“Cyclin D1 has long been recognized as a key oncogenic driver across many solid tumors and hematologic malignancies, yet it has remained an elusive direct therapeutic target,” said Marie Evangelista, Ph.D., senior vice president and head of cancer biology at Circle Pharma. “Our MXMO™ platform has allowed us to design a novel macrocyclic molecule, CID-165, with the precision and selectivity needed to directly block cyclin D1-Rb signaling while minimizing effects on related cyclins, such as cyclin D3, an approach aimed at reducing side effects commonly observed with dual CDK4/6 inhibitors.”
“Despite the transformative impact of CDK4/6 inhibitors for the treatment of ER-positive breast cancer, many patients eventually experience disease progression or adverse events that impact their quality of life,” said Anne Borgman, M.D., chief medical officer of Circle Pharma. “CID-165 is designed to address these limitations through selective inhibition of cyclin D1, a central driver of tumor proliferation, while avoiding adverse events associated with broader CDK4/6 blockade. We look forward to advancing CID-165 toward IND submission in late 2026 and potentially translating the compelling preclinical activity into benefit for patients.”
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Steve Klass
1AB
SOUTH SAN FRANCISCO, CA, December 1, 2025 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced the appointment of Anne E. Borgman, M.D., as chief medical officer. Dr. Borgman is an accomplished chief medical officer, business executive, scientific advisor and board director with more than 20 years of experience devising and executing clinical development strategies that have led to multiple oncology drug approvals.
“Dr. Borgman joins Circle with an established track record of leading clinical development teams to successful oncology drug approvals in both the U.S. and EU. Her ability to translate strong science into meaningful therapies for patients is exceptional,” said David J. Earp, J.D., Ph.D., president and chief executive officer of Circle Pharma. “Her leadership and deep experience will be instrumental as we continue the clinical development of our first-in-class cyclin A/B RxL inhibitor, CID-078, advance our cyclin D1 into the clinic, and prepare for the next stages of growth at Circle.”
“Circle Pharma’s MXMO™ platform is opening the door to a promising new class of targeted macrocycle therapies, with the potential to address some of the most challenging and impactful cancer targets such as the cyclins,” said Dr. Borgman. “I’m thrilled to join this talented team and to help guide the clinical development of programs that could make a real difference for patients with few treatment options.”
Prior to joining Circle, Dr. Borgman served as chief medical officer of Sutro Biopharma, where she advanced the company’s lead asset into pivotal trials in ovarian cancer and infant leukemia. Before that, Dr. Borgman served as vice president and therapeutic area lead, oncology, hematology, and transplant, at Jazz Pharmaceuticals, where she was responsible for global drug development for four marketed products (Defitelio®, VYXEOS ®, ZEPZELCA® and RYLAZE®), and drug development plans for several emerging targets. Previously, Dr. Borgman was vice president, clinical research & development at Exelixis, where she helped lead the global development for cabozantinib and oversaw the development and execution of multiple Phase 3 clinical trials. She has also held leadership positions in oncology drug development at KaloBios Pharmaceuticals, Talon Therapeutics (formerly Hana Biosciences), and Abbott Laboratories, where she created the early development strategies for venetoclax and veliparib while serving as global project head.
Dr. Borgman currently serves on the board of directors of clinical-stage oncology companies NextCure, Curis, and NiKang. Dr. Borgman received an M.D. from Loyola University Chicago Stritch School of Medicine and completed a residency in pediatrics at Baylor College of Medicine and a fellowship in pediatric hematology-oncology and bone marrow transplantation from the David Geffen School of Medicine at UCLA. She received her B.S. in biochemistry from University of Illinois.
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Steve Klass
1AB
SOUTH SAN FRANCISCO, CA, November 4, 2025 – Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced management will participate in upcoming investor conferences in November:
LifeSci Growth & Innovation Summit
November 17, 2025
Participants: David J. Earp, J.D., Ph.D., president and chief executive officer; Rob Lauzen, chief financial officer
Location: London, UK
Jefferies Global Healthcare Conference – London
November 18-20, 2025
Participants: David J. Earp, J.D., Ph.D., president and chief executive officer; Rob Lauzen, chief financial officer
Location: London, UK
About Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop next-generation targeted therapies for cancer and other serious illnesses. The company’s proprietary MXMO™ platform overcomes key challenges in macrocycle drug development, enabling the creation of intrinsically cell-permeable and orally bioavailable therapies, including for historically undruggable targets. Circle Pharma’s pipeline is focused on targeting cyclins, key regulators of the cell cycle that drive many cancers. The company’s lead program, CID-078, is a cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors. Circle Pharma is based in South San Francisco, CA. For additional information, please visit us at circlepharma.com and follow us on LinkedIn and X.
Contacts:
Media:
Josie Butler
1AB
Investors:
Steve Klass
1AB